Acromegaly Treatment Is Becoming Advanced With Increasing Research and Development Activities for New Treatments

 

Acromegaly Treatment Market

Acromegaly is a rare condition in which the pituitary gland produces too much growth hormone. Overproduction of this hormone leads to abnormally large organs and bones. The condition is progressive and can progress to life-threatening complications. However, with a proper treatment, symptoms can be greatly reduced and patients can experience an improved quality of life. Treatment for acromegaly can return GH levels to normal, thus improving the patient's quality of life.

There are several treatments for acromegaly. Medications, such as somatostatin analogs (octreotide or lanreotide), can lower the levels of IGF-1, a growth hormone, and help improve the outcome of surgery. They are given by injection every two to three weeks and can be used to reduce GH levels in the body. However, this type of treatment can cause unwanted side effects, so it is not recommended for long-term treatment.

The most common acromegaly treatment is surgery. A pituitary tumor, most commonly adenoma, causes acromegaly. Surgical removal of the entire tumor or parts of it may be required, depending on its size and growth into nearby structures. Surgery for acromegaly can be complicated due to the fact that it can affect many other organs, including the bones, skin, joints, and spine.

A blood test can be performed to confirm the diagnosis of acromegaly. Growth hormone levels can be determined by measuring insulin-like growth factor 1 (IGF-1) blood levels. Growth hormone levels usually fluctuate throughout the day. A single blood sample may not be helpful for diagnosis. A glucose-sugar solution can help in this case. However, glucose-sugar-induced growth hormone levels are not helpful for the diagnosis of acromegaly.

The goal of Acromegaly Treatment is to reduce the size of the acromegaly tumor and improve the quality of life. This treatment can reduce the amount of excessive sweating, improve type 2 diabetes, and help restore normal eyesight. Although life expectancy decreases after acromegaly, successful treatment can restore life expectancy and quality of living. Along with medications, acromegaly treatment may involve surgery, drug therapy, or combination of all three. In June 2020, the U.S. Food and Drug Administration (FDA), granted approval to an oral treatment for acromegaly, the somatostatin analogue octreotide, as a long-term maintenance treatment. 

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