Prostate Cancer Therapeutics Availability Has Increased In the Market Due To Rise in Focus on Targeted Drug Development

 

Prostate Cancer Therapeutics Market

The increasing focus on targeted drug development and favorable regulatory policies have resulted in an increase in the number of prostate cancer therapeutics available. Some men may benefit from hormonal therapy in combination with radiation or surgery. Newer forms of hormone therapy are increasingly being used in advanced disease and have shown some promise. With the population aging rapidly, incidences of the disease are expected to increase.

However, there are some limitations with these therapies. For example, some doctors suspect they may have missed the high-grade cancer. As a result, they may opt for radical surgery or radiation. However, this may be overkill for patients with low-grade cancer. MRI-targeted biopsy is a new technique developed by NCI scientists. This technique uses computer technology to fuse ultrasound and MRI images to pinpoint areas of possible cancer. It is not currently practical to use real-time guidance for prostate biopsy, however, it enables doctors to conduct a biopsy of suspected cancer regions.

The neuroendocrine cells present in the prostate exhibit distinct morphologic features, including those of neurons. Inhibiting the activity of AR has been shown to promote the differentiation of cancer cells. These agents may have different effects on prostate cancer stem cells, which are thought to be responsible for the progression of the disease. The effectiveness of HDACIs is largely dependent on the specificity of the treatment. However, the potential for neuroendocrine therapies is significant.

Despite significant progress in the management of prostate cancer, many patients still fail to respond to the standard agents. Thus, new molecular targets for Prostate Cancer Therapeutics are necessary for better patient outcomes. Activation of small GTPases (SGLTs) is a key aspect of most of the upregulated receptors in prostate cancer. It has the potential to be an important therapeutic intervention for advanced prostate cancer patients. It has also shown promise in reducing prostate cancer burden. In March 2022, Novatris Pluvicto received approval from US Food and Drug Administration as a targeted radioligand therapy for treating progressive PSMA-positive metastatic castration –resistant prostate cancer.

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